the central MIKAIA® learning portal
get inspired
(note: in February 2024 MICAIA was renamed to MIKAIA®)
MIKAIA University is the central MIKAIA® learning portal. Here you can find various app notes and video tutorials that describe typical MIKAIA® workflows either from a technical or medical perspective. The underlying AI technologies are described in our scientific publications. The latest software changes are documented in the MIKAIA® Changelog.
As we are continuously adding more content, please check back frequently or subscribe to the MIKAIA® newsletter, where we announce newly released app notes.
Apps & AIs
MIKAIA® 2.4 (released Sep 2025) includes 20 apps, 10 of which work for both brightfield and fluorescent scans.
The AI Author App and Plug-in your own AI App can be used to develop additional user-specific apps.

More details, including a description of each app, are available here.
MIKAIA® is for Research Use Only (RUO).

Frequently Asked Questions
Navigating a flexible digital pathology and spatial biology image analysis software like MIKAIA® can bring up many questions — perhaps even before you get started. If our FAQs don’t answer your question, don’t hesitate to drop us a line.
First Steps
If you just installed MIKAIA® and want to get started, this blog post will guide you through the essentials: MIKAIA® Introduction & First Steps

MIKAIA University App Notes & Concepts
MIKAIA University App Notes are blog articles, where we describe a particular MIKAIA® app or a medical use case in a step-by-step fashion. They illustrate how MIKAIA® can be used to make discoveries or automate quantitative analysis in Digital Pathology & Spatial Biology. Our app notes typically describe what the expected input images look like and what quantitative outputs can be generated. They contain many screenshots and explain the concepts or in some cases even the technical background of the image analysis apps.
We are frequently releasing new app notes. Here are the most recent additions:



Gallery
IHC cell quantification
AI gallery
IHC cell analysis examples for various IHC markers and organs.

MIKAIA® Editions
Don’t worry about selecting which apps you want to purchase. You do not need to select each individual app. Currently, three feature sets are available:
- MIKAIA® lite (free)
- MIKAIA® studio
- MIKAIA® studio + AI App Bundle
If you’d like to try out the MIKAIA® apps on a temporary basis or request a quote, please feel free to email us at mikaia@iis.fraunhofer.de.

User Manual

Download the detailed 100+ pages user manual:
It is also included in the free MIKAIA® installer (download here) and available from within MIKAIA® by clicking “User Manual” in the main “Help” menu.
MIKAIA University Video Tutorials
These and further videos are available in the MIKAIA® YouTube playlist.
Workflow: How to creat a new AI with the AI Author App and then batch-analyze an entire dataset.






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