MIKAIA® studio v3.1 includes native support for viewing and analyzing multi-omics datasets created with Singular Genomics’ G4X™ instrument. G4X features 500plex transcriptomics, 18plex proteomics and same-slide...
Author - Volker Bruns
Volker Bruns
Cell Typing and Neighborhood Analysis of mIF 20plex Tonsil Tissue Using MGI VisiOmics and MIKAIA studio
The collaboration aims to show how researchers can use VisiOmics image data within MIKAIA® workflows for cell segmentation, phenotyping, and spatial analysis. This work supports greater flexibility in downstream...
Xenium Analysis with the MIKAIA Cell x Gene App
The MIKAIA® Cell x Gene App can be used to analyze FISH (or similar, e.g., RNAscope), CISH, or spatial transcriptomics scans, including Xenium by 10x Genomics. For Xenium data in particular, this app is the right...
CISH App Explained
Chromogenic in situ hybridization (CISH) is used to detect specific DNA or RNA sequences in tissue samples. It uses enzyme-based staining rather than fluorescence (FISH), allowing for high-resolution imaging...
MIKAIA’s Slide Alignment: An Overview
With the MIKAIA® 3 release (April 2026), MIKAIA® received a new multi-omics slide alignment module, “MIKAIA® Slide Align“. Based on a 3-phase registration process, the last one being a non-rigid deformation...
Manual Spatial Proteomics: Fusing Cycles into OME-TIF was Never Easier
Spatial Proteomics was named the Nature Method of the Year 2024. One predominant method is Cyclic Immunofluorescence (CycIF). Here, a tissue sample is stained and scanned during a first cycle. Next, the stain is...
MIKAIA’s Universal IHC Cell AI App explained
The Universal IHC Cell AI App features a universal subcellular IHC cell AI that is compatible with a wide range of markers, tissues, and cell types. Our 23-minute video tutorial guides MIKAIA® step by step through the...
MIKAIA mIF Cell Segmentation AI Gallery
This gallery highlights MIKAIA's mIF Cell Segmentation in the FL Cell Analysis App, featuring various examples and an overview of the AI's three segmentation modes and various cell typing options.
MIKAIA First Steps
New to MIKAIA®? This blog post is here to help you get started on your first steps.
MIKAIA IHC Cell Quantification AI Gallery
This gallery illustrates for a range of different tissue types and IHC markers the cell analysis quality of MIKAIA‘s IHC Cell Detection App. The app first unmixes the stain components, then uses an AI to delineate...
