With the upcoming MIKAIA® 3 release (scheduled for Q1 2026), MIKAIA® will receive a new multi-omics slide alignment module, “MIKAIA® Slide Align“. Based on a 3-phase registration process, the last one being a non-rigid deformation for...
Spatial Proteomics was named the Nature Method of the Year 2024. One predominant method is Cyclic Immunofluorescence (CycIF). Here, a tissue sample is stained and scanned during a first cycle. Next, the stain is bleached away, and the sample is...
This gallery highlights MIKAIA's mIF Cell Segmentation in the FL Cell Analysis App, featuring various examples and an overview of the AI's three segmentation modes and various cell typing options.
Browse through our Spatial Biology article collection around spatial proteomics and spatial transcriptomics, with a focus on data science.
With the upcoming MIKAIA® 3 release (scheduled for Q1 2026), MIKAIA® will receive a new multi-omics slide alignment module, “MIKAIA® Slide Align“. Based on a 3-phase registration process, the last one being...
Spatial Proteomics was named the Nature Method of the Year 2024. One predominant method is Cyclic Immunofluorescence (CycIF). Here, a tissue sample is stained and scanned during a first cycle. Next, the stain is...
This gallery highlights MIKAIA's mIF Cell Segmentation in the FL Cell Analysis App, featuring various examples and an overview of the AI's three segmentation modes and various cell typing options.
New to MIKAIA®? This blog post is here to help you get started on your first steps.
In this year’s Trillium Pathology, Volker Bruns (Fraunhofer IIS), Sonja Fritzsche (Max Delbrück Center for Molecular Medicine), and Fabian Coscia (Max Delbrück Center for Molecular Medicine) have contributed an article...
A strong suit of MIKAIA® is its wide portfolio of analysis apps for multiplexed immunofluorescence (mIF) / spatial proteomics. It can be used for both low-plex and high-plex panels and is compatbile with image formats...
How can the advanced AI analysis capabilities of MIKAIA® assist researchers and clinicians in analyzing their digital pathology and spatial biology data? This talk provides an overview of MIKAIA’s advanced...
This MIKAIA® app note demonstrates how to analyze a 47-plex spatial proteomics scan created with MACSima ™ (by Miltenyi Biotec), utilizing sequential immunofluorescence for the analysis: Instrument: MACSima™ by Miltenyi...
The MIKAIA® Cellular Neighborhood App can yield statistics about the cellular microenvironment, i.e., identify cell niches or cellular communities. This presents a type of spatial analysis of cell populations detected...
CODEX, now called PhenoCycler, by Akoya Biosciences, along with other sequential immunofluorescence technologies (e.g., Lunaphore (Comet), Miltenyi Biotech (MACSima), Leica Microsystems (Cell DIVE), or other vendors)...
© Fraunhofer IIS · 2026
Volker Bruns
Grit Nickel
Michaela Benz