This MIKAIA® App Note shows how to quantify tumor in proximity to nerve fibers (perineural invasion) in a IHC duplex-stained tissue section, where nerves appear red (antigen: S100) and tumor brown (antigen:...
Tag - MIKAIA Application Note
Volker Bruns
Annotation Concepts in MIKAIA for Whole-Slide-Images
The first step to creating a supervised Digital Pathology AI is to annotate whole-slide-images. MIKAIA uses various annotation concepts. Working with MIKAIA is easier when these annotation concepts are known and...
MIKAIA® University
MIKAIA® University is the central MIKAIA® learning portal. Here you can find various App Notes and Video Tutorials that describe typical MICAIA® workflows either from a technical or medical perspective. As we are...
MIKAIA HER2 FISH App
About 20 % to 25 % of breast cancers depend on amplification and overexpression of the gene human epidermal growth factor receptor 2 (HER2). The HER2 overexpression status will initially be assessed by...
Nathalie Falk
IHC Profiler in MIKAIA – Assessing New IHC Assay Using Multi-organ TMA
When designing a new immunohistochemistry (IHC) assay, a quantitative assessment of how it “responds” in different tissues of various organs is insightful and helps optimizing the assay in an objective...
MIKAIA Spatial Clustering App
Tumor cells dynamically interact with their microenvironment to stimulate cancer development, progression, and metastasis. To understand the biology of the tumor-immune interactions, it is essential to identify tumoral...
MIKAIA-Analysis of Human Pancreas 4plex Scanned with NanoString GeoMx DSP
In this MIKAIA University application note, we guide you through the analysis of a common use case, coexpression of marker combinations in islets of Langerhans and surrounding tissue in a pancreas 4plex imaged with...
MIKAIA-Analysis of Human Tonsil 15plex Imaged with Akoya PhenoCycler-Fusion
In this MIKAIA University application note, we guide you through the analysis of a common use case, coexpression of marker combinations in lymphoid follicles and interfollicular tissue in a tonsil 15plex imaged with...
MIKAIA FL Colocalization App
MIKAIA University Application Note: Analyzing multiplexed immuno fluorescent (mIF) slides MIKAIA has good support for viewing, annotating and analyzing multi-plexed (aka high-plex, aka hyper-plex) whole-slide images...
MIKAIA AI Authoring App
MIKAIA University Application Note: Interactively training an AI with the AI Authoring App — programming-free and from just a few example annotations By design, researchers often have unique questions that they...
