Chromogenic in situ hybridization (CISH) is used to detect specific DNA or RNA sequences in tissue samples. It uses enzyme-based staining rather than fluorescence (FISH), allowing for high-resolution imaging, quantification, and analysis under...
This MIKAIA® University app note demonstrates how to quickly and interactively train your own AI using just a few training annotations, all in a matter of minutes. In the app center, select the Segmentation AI Author App, click “+” to...
This MIKAIA® University app note illustrates how to interactively train a new H&E segmentation AI with serial sections, without having to annotate tumor regions. Instead, an IHC epithelial marker (pan-cytokeratin AE1/AE3) is thresholded through...
Browse through our collection of articles and interviews on Digital Pathology, Computational Pathology, and AI as well as app notes for the MIKAIA® whole-slide image analysis software for researchers.
MIKAIA® University Application Note: Interactively training an AI with the AI Authoring App — programming-free and from just a few example annotations By design, researchers often have unique questions that they...
MIKAIA® University Application Note: Immune cell infiltration in tumor micro environment (TME) List of other articles on analysis of IHC stains: new (Oct. 2025): IHC Cell Detection App explained (23min video tutorial...
You want to develop your own digital pathology AI? The following MIKAIA® University application note explains how to create an AI training dataset using the MIKAIA® Tile Export App. The first step is to create a dataset...
The 2023 congress of the German Society of Pathology (DGP) was hosted by Tübingen’s Pathology Director Prof. Dr. Falko Fend. It took place June 1st-3rd in the congress center in sunny Leipzig. Last I’ve...
Physicians expect biopsy or tumor resection results from pathology daily to make diagnoses and find appropriate therapies for the patients. A 2016 interview-based study of internal medicine specialists addresses supply...
Two of our closest clinical partners, Prof. Dr. Arndt Hartmann, head of the Institute of Phathology, and Adjunct Professor Dr. Carol Geppert, head of cytology and digital pathology at the Universitätsklinikum Erlangen...
Find out more about the Digital Pathology application in the ADA Lovelace Center. Interview with Dr. Michaela Benz on AI-based diagnostical support in the ADA Lovelace Center. Read more interesting articles on AI...
Cell sorting is an established and powerful technology in molecular biological research to distinguish and isolate specific cell types from a heterogeneous cell population. Isolation of the specific cell populations...
Everyone is talking about spatial biology. But what is spatial biology really? It’s an umbrella term for a new set of technologies, the most prominent ones being spatial transcriptomics and proteomics, but also spatial...
Many recent breakthroughs in cancer therapy fall into the category of personalized medicine. Cancers are characterized more deeply using Molecular Pathology. Another revolutionizing technology that opens up new...
© Fraunhofer IIS · 2026
Volker Bruns
Michaela Benz
Nathalie Falk
Hannah Merz