Life Science Spatial Biology

Analyzing Singular Genomics G4X™ Multi-Omics Datasets with MIKAIA

MIKAIA® studio v3.1 includes native support for viewing and analyzing multi-omics datasets created with Singular Genomics’ G4X™ instrument. G4X features 500plex transcriptomics, 18plex proteomics and same-slide morphology via fluorescent...

Volker Bruns

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Life Science Spatial Biology

Cell Typing and Neighborhood Analysis of mIF 20plex Tonsil Tissue Using MGI VisiOmics and MIKAIA studio

The collaboration aims to show how researchers can use VisiOmics image data within MIKAIA® workflows for cell segmentation, phenotyping, and spatial analysis. This work supports greater flexibility in downstream analysis, helping laboratories...

Volker Bruns

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Life Science MIKAIA University Spatial Biology

Xenium Analysis with the MIKAIA Cell x Gene App

The MIKAIA® Cell x Gene App can be used to analyze FISH (or similar, e.g., RNAscope), CISH, or spatial transcriptomics scans, including Xenium by 10x Genomics. For Xenium data in particular, this app is the right choice, supporting three types of...

Volker Bruns

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Category - Life Science

Common category to topics from Digital Pathology, Computational Pathology, Spatial Biology as well as applications and technologies left and right.

Digital Pathology

Spatial Biology

Digital Pathology Life Science

IHC Staining and Molecular Biomarkers

Cancer is a major cause of mortality worldwide, and the evaluation of predictive and prognostic markers is crucial in its pathologic assessment. Immunohistochemistry (IHC) is commonly used to evaluate biomarker status...

Nathalie Falk

July 21, 2024

Digital Pathology Life Science MIKAIA University

MIKAIA: Build H&E Analysis using Multiple AIs

MIKAIA® is specifically designed for researchers in academia, CROs, biotech, pharma. One of the challenges is that researchers by design do unique things. For this reason, MIKAIA® apps do not represent individual side...

Volker Bruns

July 17, 2024

Digital Pathology Life Science MIKAIA University

MIKAIA: Differential IHC Cell Detection by ROI

This article is based on a our presentation “IHC Cell Analysis — More than just Cell Counting: A proposed Workflow” at the European Conference for Digital Pathology (ECDP) 2024 in Vilnius, Lithuania...

Volker Bruns

July 16, 2024

DNA string visualizing our Medical Buzzwords glossary

Digital Health Digital Pathology Spatial Biology

Glossary of Medical Buzzwords

In the fast-paced world of healthcare, staying informed about the latest medical buzzwords and trends is essential to understanding where the future of medicine is heading. From computer-aided diagnosis and personalized...

Julia Fröhlich

July 15, 2024

Digital Pathology Life Science

The Digital Pathologist’s Cockpit: Image Management Systems (IMS) – Free Download of List of IMSes

In conventional pathology, the pathologists mostly interacted with their LIS (lab information system). Synonyms are PIS (pathology information system) or LIMS (laboratory information & management system)...

Volker Bruns

July 9, 2024

Spatial Biology

List of Commercial Spatial Biology Instruments, Assays & Softwares

Spatial Biology is a big hype right now and a rapidly growing discipline, especially spatial proteomics and spatial transcriptomics. It is the intersection of anatomical pathology where the morphology of tissue is...

Volker Bruns

July 9, 2024

Digital Pathology Life Science MIKAIA University Spatial Biology

WSI and Annotation File Format I/O Support in MIKAIA

MIKAIA® supports various I/O formats, find out which ones. Importable whole-slide-image file formats Format / VendorCommentsOME-TIFFBrightfield and fluorescence. Z-stacks and timelines supported (mutually-exclusive). No...

Volker Bruns

May 29, 2024

Organizing data via a plattform is important while collaborating in a clinical trial

Digital Health Life Science Medical Data Space

Better together – Collaboration in a Clinical Trial

What does a collaboration with Fraunhofer IIS actually look like during a clinical trial study? The following interview may give a clearer picture. We spoke to Sebastian Eckl, one of the founders of ProCarement GmbH...

Anna Chiwona

May 7, 2024

Digital Pathology MIKAIA University

MIKAIA: Quantifying Perineural Invasion in Duplex IHC

This MIKAIA® App Note shows how to quantify tumor in proximity to nerve fibers (perineural invasion) in a IHC duplex-stained tissue section, where nerves appear red (antigen: S100) and tumor brown (antigen:...

Volker Bruns

April 3, 2024

Digital Pathology

Ultimate Guide: 10 Things to Know about the Transformational Impact of Digital Pathology

Digital Pathology is a new data source to transform medicine Medscape – Oct 15, 2014. This was the hook line of a 2014 article in Medscape we stumbled across the other day. Ten years later...

Grit Nickel

January 25, 2024

Category - Life Science

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