Life Science MIKAIA University Spatial Biology

Xenium Analysis with the MIKAIA Cell x Gene App

The MIKAIA® Cell x Gene App can be used to analyze FISH (or similar, e.g., RNAscope), CISH, or spatial transcriptomics scans, including Xenium by 10x Genomics. For Xenium data in particular, this app is the right choice, supporting three types of...

Volker Bruns

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Digital Pathology Life Science MIKAIA University

CISH App Explained

Chromogenic in situ hybridization (CISH) is used to detect specific DNA or RNA sequences in tissue samples. It uses enzyme-based staining rather than fluorescence (FISH), allowing for high-resolution imaging, quantification, and analysis under...

Volker Bruns

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Digital Pathology Life Science MIKAIA University

Train your own AI with the Segmentation AI Author: Ovarian Cancer Example

This MIKAIA® University app note demonstrates how to quickly and interactively train your own AI using just a few training annotations, all in a matter of minutes. In the app center, select the Segmentation AI Author App, click “+” to...

Michaela Benz

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Category - Life Science

Common category to topics from Digital Pathology, Computational Pathology, Spatial Biology as well as applications and technologies left and right.

Digital Pathology

Spatial Biology

Digital Pathology Life Science MIKAIA University

MIKAIA: Differential IHC Cell Detection by ROI

This article is based on a our presentation “IHC Cell Analysis — More than just Cell Counting: A proposed Workflow” at the European Conference for Digital Pathology (ECDP) 2024 in Vilnius, Lithuania...

Volker Bruns

July 16, 2024

DNA string visualizing our Medical Buzzwords glossary

Digital Health Digital Pathology Spatial Biology

Glossary of Medical Buzzwords

In the fast-paced world of healthcare, staying informed about the latest medical buzzwords and trends is essential to understanding where the future of medicine is heading. From computer-aided diagnosis and personalized...

Julia Fröhlich

July 15, 2024

Digital Pathology Life Science

The Digital Pathologist’s Cockpit: Image Management Systems (IMS) – Free Download of List of IMSes

In conventional pathology, the pathologists mostly interacted with their LIS (lab information system). Synonyms are PIS (pathology information system) or LIMS (laboratory information & management system)...

Volker Bruns

July 9, 2024

Spatial Biology

List of Commercial Spatial Biology Instruments, Assays & Softwares

Spatial Biology is a big hype right now and a rapidly growing discipline, especially spatial proteomics and spatial transcriptomics. It is the intersection of anatomical pathology where the morphology of tissue is...

Volker Bruns

July 9, 2024

Digital Pathology Life Science MIKAIA University Spatial Biology

WSI and Annotation File Format I/O Support in MIKAIA

MIKAIA® supports various I/O formats, find out which ones. Importable whole-slide-image file formats Format / VendorCommentsOME-TIFFBrightfield and fluorescence. Z-stacks and timelines supported (mutually-exclusive). No...

Volker Bruns

May 29, 2024

Organizing data via a plattform is important while collaborating in a clinical trial

Digital Health Life Science Medical Data Space

Better together – Collaboration in a Clinical Trial

What does a collaboration with Fraunhofer IIS actually look like during a clinical trial study? The following interview may give a clearer picture. We spoke to Sebastian Eckl, one of the founders of ProCarement GmbH...

Anna Chiwona

May 7, 2024

Digital Pathology MIKAIA University

MIKAIA: Quantifying Perineural Invasion in Duplex IHC

This MIKAIA® App Note shows how to quantify tumor in proximity to nerve fibers (perineural invasion) in a IHC duplex-stained tissue section, where nerves appear red (antigen: S100) and tumor brown (antigen:...

Volker Bruns

April 3, 2024

Digital Pathology

Ultimate Guide: 10 Things to Know about the Transformational Impact of Digital Pathology

Digital Pathology is a new data source to transform medicine Medscape – Oct 15, 2014. This was the hook line of a 2014 article in Medscape we stumbled across the other day. Ten years later...

Grit Nickel

January 25, 2024

Digital Pathology MIKAIA University

Annotation Concepts in MIKAIA for Whole-Slide-Images

The first step to creating a supervised Digital Pathology AI is to annotate whole-slide-images. MIKAIA® uses various annotation concepts, and understanding these concepts will make your experience with MIKAIA® much...

Volker Bruns

January 5, 2024

Life Science

AI Will Survive: Integrating Artificial Intelligence in the Life Sciences

AI is on the rise in pretty much every scientific field (at least it feels that way). We talked to Nathalie Falk, one of the voices behind the MIKAIA University application notes, molecular biologist with a PhD in...

Volker Bruns

Grit Nickel

December 11, 2023

Category - Life Science

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