SMART SENSING insights
Just like Stuttgart Public Library, MIKAIA University is a hub for learning.

MIKAIA University

the central MIKAIA® learning portal

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(note: in February 2024 MICAIA was renamed to MIKAIA®)

MIKAIA University is the central MIKAIA® learning portal. Here you can find various app notes and video tutorials that describe typical MIKAIA® workflows either from a technical or medical perspective. The underlying AI technologies are described in our scientific publications. The latest software changes are documented in the MIKAIA® Changelog.

As we are continuously adding more content, please check back frequently or subscribe to the MIKAIA® newsletter, where we announce newly released app notes.

Apps & AIs

MIKAIA® 2.4 (released Sep 2025) includes 20 apps, 10 of which work for both brightfield and fluorescent scans.
The AI Author App and Plug-in your own AI App can be used to develop additional user-specific apps.

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More details, including a description of each app, are available here.
MIKAIA® is for Research Use Only (RUO).

MIKAIA FAQs with Logo printed on a colorful background

Frequently Asked Questions

Navigating a flexible digital pathology and spatial biology image analysis software like MIKAIA® can bring up many questions — perhaps even before you get started. If our FAQs don’t answer your question, don’t hesitate to drop us a line.

First Steps

If you just installed MIKAIA® and want to get started, this blog post will guide you through the essentials: MIKAIA® Introduction & First Steps

MIKAIA First steps visualized by foot prints on the MIKAIA gradient

MIKAIA University App Notes & Concepts

MIKAIA University App Notes are blog articles, where we describe a particular MIKAIA® app or a medical use case in a step-by-step fashion. They illustrate how MIKAIA® can be used to make discoveries or automate quantitative analysis in Digital Pathology & Spatial Biology.

Browse All App Notes

We release new content regularly – here are the latest additions:

MIKAIA® Editions

Don’t worry about selecting which apps you want to purchase. You do not need to select each individual app. Currently, three feature sets are available:

  1. MIKAIA® lite (free)
  2. MIKAIA® studio
  3. MIKAIA® studio + AI App Bundle

If you’d like to try out the MIKAIA® apps on a temporary basis or request a quote, please feel free to email us at mikaia@iis.fraunhofer.de.

Overwiew of MIKAIA apps and their respective edition

User Manual

Download the detailed 100+ pages user manual:

Download Manual

It is also included in the free MIKAIA® installer (download here) and available from within MIKAIA® by clicking “User Manual” in the main “Help” menu.

MIKAIA University Video Tutorials

These and further videos are available in the MIKAIA® YouTube playlist.

Workflow: How to creat a new AI with the AI Author App and then batch-analyze an entire dataset.

Workflow of 3 apps: Detect tumor in colon section. Then classify cells in tumor area. Then compute cell-cell connections and highlight tumor-infiltrating lymphocytes (TILs).
Example workflow of 3 Apps: Train AI to detect mucosa. Then run Crypt AI only in mucosa mask. Then detect cells and group by intra-crypt vs. inter-crypt. View app note.
IHC analysis of murine lung tissue (FoxP3): DAB+ cells are detected and then grouped by inside metastasis vs outside metasis vs in invasive margin. View app note.

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Volker Bruns

Volker is a digital pathology and spatial biology enthusiast with a computer science background. Volker and his team develop commercial image analysis software for digital pathology and offer contract development, as well as image analysis as a service in the life sciences.

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