This gallery illustrates for a range of different tissue types and IHC markers the cell analysis quality of MIKAIA‘s IHC Cell Detection App. The app first unmixes the stain components, then uses an AI to delineate cells, then computes the...
NEW: This article and the downloadable list was updated on July 15th 2025 2022 – 2024 have been breakthrough years for AI in digital pathology. Many new startups, backed by lots of venture capital, as well as established vendors have released...
How can the advanced AI analysis capabilities of MIKAIA® assist researchers and clinicians in analyzing their digital pathology and spatial biology data? This talk provides an overview of MIKAIA’s advanced features, highlighting useful...
Browse through our collection of articles and interviews on Digital Pathology, Computational Pathology, and AI as well as app notes for the MIKAIA® whole-slide image analysis software for researchers.
MIKAIA® AI Author used for Digital Pathology batch analysis
We have contributed two article’s to this year’s Trillium Pathology issue. Here are the abstracts, with links to the full articles: V. Bruns, Programming-free Image-Analysis Workflows for IHC, IF and Spatial...
This app note describes the MIKAIA Plugin API. It can be used by bioinformaticians to plug in their own AI script, e.g., written in Python or any other language, into MIKAIA® and this way put their AI into the hands of...
Cancer is a major cause of mortality worldwide, and the evaluation of predictive and prognostic markers is crucial in its pathologic assessment. Immunohistochemistry (IHC) is commonly used to evaluate biomarker status...
MIKAIA® is specifically designed for researchers in academia, CROs, biotech, pharma. One of the challenges is that researchers by design do unique things. For this reason, MIKAIA® apps do not represent individual side...
This article is based on a our presentation “IHC Cell Analysis — More than just Cell Counting: A proposed Workflow” at the European Conference for Digital Pathology (ECDP) 2024 in Vilnius, Lithuania...
In the fast-paced world of healthcare, staying informed about the latest medical buzzwords and trends is essential to understanding where the future of medicine is heading. From computer-aided diagnosis and personalized...
In conventional pathology, the pathologists mostly interacted with their LIS (lab information system). Synonyms are PIS (pathology information system) or LIMS (laboratory information & management system)...
MIKAIA® supports various I/O formats, find out which ones. Importable whole-slide-image file formats Format / VendorCommentsOME-TIFFBrightfield and fluorescence. Z-stacks and timelines supported (mutually-exclusive). No...
This MIKAIA® App Note shows how to quantify tumor in proximity to nerve fibers (perineural invasion) in a IHC duplex-stained tissue section, where nerves appear red (antigen: S100) and tumor brown (antigen:...
© Fraunhofer IIS 2025
Volker Bruns
Michaela Benz
Nathalie Falk
Julia Fröhlich