In this MIKAIA® University app note, we will walk you through the necessary steps to unlock the features that are locked in MIKAIA® lite. Whether you’re evaluating MIKAIA® studio or have purchased a license...
Tag - MIKAIA® App Note
MIKAIA University App Notes are blog articles that provide a detailed, step-by-step demonstration of specific MIKAIA® apps or medical use cases. They illustrate how MIKAIA® can be used to make discoveries or automate quantitative analysis in Digital Pathology & Spatial Biology.
Grit Nickel
MIKAIA IHC Cell Quantification AI Gallery
This gallery illustrates for a range of different tissue types and IHC markers the cell analysis quality of MIKAIA‘s IHC Cell Detection App. The app first unmixes the stain components, then uses an AI to delineate...
Volker Bruns
Overview of MIKAIA’s Spatial Analysis Apps for Multiplexed Immunofluorescence Slides
A strong suit of MIKAIA® is its wide portfolio of analysis apps for multiplexed immunofluorescence (mIF) / spatial proteomics. It can be used for both low-plex and high-plex panels and is compatbile with image formats...
More than AI-based Analysis: Discover Spatial Patterns in your Whole Slide Images with MIKAIA
How can the advanced AI analysis capabilities of MIKAIA® assist researchers and clinicians in analyzing their digital pathology and spatial biology data? This talk provides an overview of MIKAIA’s advanced...
Michaela Benz
Analyzing MACSima 47-plex mIF with MIKAIA: AI Cell Segmentation + Cell Typing + Cell-cell Connections + Cellular Neighborhoods
This MIKAIA® app note demonstrates how to analyze a 47-plex spatial proteomics scan created with MACSima ™ (by Miltenyi Biotec), utilizing sequential immunofluorescence for the analysis: Instrument: MACSima™ by Miltenyi...
High Content Imaging: Analyzing Ex-Vivo Drug Response Assays with MIKAIA
Researchers at the Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM) have developed PEDRA: Platform for Ex-Vivo Drug Response Assays. Up to 100 compounds are tested in parallel on primary patient...
MIKAIA Cellular Neighborhood App Explained
The MIKAIA® Cellular Neighborhood App can yield statistics about the cellular microenvironment, i.e., identify cell niches or cellular communities. This presents a type of spatial analysis of cell populations detected...
Proximity Analysis: Quantifying Cell Subpopulations in Vicinity of Intratumoral Microdevice (IMD)
The Laboratory for Bio-Micro Devices at Brigham and Women’s Hospital () develops drug releasing implantable intratumoral microdevices (IMD) [1]. Using MIKAIA®, they want to examine in a quantitative fashion how...
Programming-free Single Cell Analysis of CODEX TMA with MIKAIA
CODEX, now called PhenoCycler, by Akoya Biosciences, along with other sequential immunofluorescence technologies (e.g., Lunaphore (Comet), Miltenyi Biotech (MACSima), Leica Microsystems (Cell DIVE), or other vendors)...
Quantify Histological Growth Pattern or Spatial Heterogeneity with the Grid Analysis App
Result of Grid Analysis App shows histological growth pattern and spatial heterogeneity
